Reduced susceptibility to dextran sulphate sodium-induced colitis in the interleukin-2 heterozygous (IL-2+/-) mouse
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چکیده
منابع مشابه
Reduced susceptibility of mice overexpressing transforming growth factor alpha to dextran sodium sulphate induced colitis.
BACKGROUND Transforming growth factor alpha (TGF-alpha) knockout mice have increased susceptibility to dextran sodium sulphate (DSS) induced colitis. AIM To substantiate the findings that TGF-alpha is a key mediator of colonic mucosal protection and/or repair mechanisms by evaluating the susceptibility of mice overexpressing TGF-alpha to DSS induced colitis. METHODS TGF-alpha overexpression...
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ژورنال
عنوان ژورنال: Immunology
سال: 2005
ISSN: 0019-2805,1365-2567
DOI: 10.1111/j.1365-2567.2005.02123.x